New research published in Acta Obstetricia et Gynecologica Scandinavica suggests that babies born via cesarean section delivery may face a higher risk of developing Crohn’s disease later in life.
In the national population-based study, all full-term individuals registered in the Medical Birth Register in Sweden between 1990 and 2000 were followed until 2017. Among 1,102,468 individuals, of whom 11.6% were delivered by cesarean section and 88.4% were vaginally delivered, cesarean section was associated with a 14% higher risk of developing Crohn's disease after adjusting for confounding factors. No associations between delivery mode and appendicitis, ulcerative colitis, cholecystitis, or diverticulosis were found.
“Our study is the largest in this field, showing new interesting associations between cesarean section and increased risk later in life for Crohn’s disease. We hypothesize that the underlying mechanism could be the gut microbiome, but further studies will have to confirm this,” said senior author Anna Löf Granström, of the Karolinska Institute, in Sweden.
Additional Information
Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/aogs.14427
About Journal
Published monthly, Acta Obstetricia et Gynecologica Scandinavica is an international journal dedicated to providing the very latest information on the results of both clinical, basic and translational research work related to all aspects of women’s health from around the globe. The journal regularly publishes commentaries, reviews, and original articles on a wide variety of topics including: gynecology, pregnancy, birth, female urology, gynecologic oncology, fertility and reproductive biology.
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