In a study in Arthritis & Rheumatology of people with hand osteoarthritis, higher body mass index was associated with greater pain severity in the hands, feet, knees, and hips.
In the study of 281 patients, the observed associations of body mass index with hand pain and total body joint pain seemed to involve certain inflammatory markers (leptin and high-sensitivity C-reactive protein, respectively).
“Our results highlight the complexity of pain in hand osteoarthritis. Obesity is not only leading to pain through increased loading of joints in the lower extremities, but seems to have systemic effects leading to pain in the hands and overall body,” said lead author Marthe Gløersen, MD, of Diakonhjemmet Hospital, in Norway.
Additional Information
Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/art.42056
About Journal
Arthritis & Rheumatology, an official journal of the American College of Rheumatology, is a peer-reviewed publication for scientists and clinicians interested in the natural history, pathophysiology, treatment, and outcome of the rheumatic diseases. The journal publishes the highest quality basic and clinical research related to the rheumatic diseases, encompassing a wide range of areas of investigative activity. In addition, Arthritis & Rheumatology publishes review articles, editorials, and other educational material intended for both researchers and clinicians.
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