A clinical trial published in Arthritis & Rheumatology recently examined whether duloxetine, a medication that is prescribed to treat depression and may also reduce chronic pain, can benefit patients with hip or knee osteoarthritis.
In the trial of patients experiencing chronic osteoarthritis-related pain in the hip or knee that did not go away with over-the-counter medications, 66 were randomized to duloxetine added to usual care and 66 were randomized to usual care alone.
The trial’s investigators found that duloxetine did not lessen pain at 3 months or 12 months.
“There was no clinically relevant effect of duloxetine added to usual care compared to usual care alone for chronic osteoarthritis pain, and it should not be implemented,” the authors wrote.
Additional Information
Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/art.42040
About Journal
Arthritis & Rheumatology, an official journal of the American College of Rheumatology, is a peer-reviewed publication for scientists and clinicians interested in the natural history, pathophysiology, treatment, and outcome of the rheumatic diseases. The journal publishes the highest quality basic and clinical research related to the rheumatic diseases, encompassing a wide range of areas of investigative activity. In addition, Arthritis & Rheumatology publishes review articles, editorials, and other educational material intended for both researchers and clinicians.
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