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What Are the Effects of Inappropriate Prescriptions in Older Adults?

05/19/2021

Individuals are often prescribed increasing numbers of medications as they age, and while many of these prescriptions are justifiable, some may be inappropriate. A recent analysis published in the British Journal of Clinical Pharmacology examined the results of all studies investigating associations between potentially inappropriate prescribing—which includes prescribing medications that may not produce benefits relative to harm and not prescribing medications that are recommended—and outcomes of older adults.

Potentially inappropriate prescribing was significantly associated with a range of health-related and system-related outcomes, including functional decline, falls, and hospital admissions due to drug-related side effects.

“Several decision support tools for quality prescribing are available; however, our analysis highlights that medication-related harm due to inappropriate prescribing remains problematic,” said lead author Alemayehu Mekonnen, PhD, of Deakin University, in Australia. “A comprehensive assessment of medication use, especially during care transitions such as at hospital discharge, is an important task to reduce medication-related harm and associated healthcare costs.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/bcp.14870

About Journal

Published on behalf of the British Pharmacological Society, the British Journal of Clinical Pharmacology features papers and reports on all aspects of drug action in humans: review articles, mini review articles, original papers, commentaries, editorials and letters. The Journal enjoys a wide readership, bridging the gap between the medical profession, clinical research and the pharmaceutical industry. It also publishes research on new methods, new drugs and new approaches to treatment. The Journal is recognised as one of the leading publications in its field. It is online only, publishes open access research through its OnlineOpen programme and is published monthly.

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at www.wiley.com.

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