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Study Links Kidney Stones with Bone Problems

03/03/2021

In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the Journal of Bone and Mineral Research

Investigators identified 531,431 patients with kidney stone disease between 2007 and 2015, and they found that 23.6% of patients had a diagnosis of osteoporosis or fracture around the time of their kidney stone diagnosis. In patients with no prior history of osteoporosis or bone analyses before their kidney stone diagnosis, 9.1% received a bone density scan after a kidney stone diagnosis, of whom 20% were subsequently diagnosed with osteoporosis. 

The findings provide support for wider use of bone density screening in individuals with kidney stones, including middle-aged and older men who may not be recognized as at-risk for osteoporosis or fracture. 

“We hope this work raises awareness regarding the possibility of reduced bone strength in patients with kidney stones. In our future work, we hope to identify which patients with kidney stones are at higher risk for osteoporosis or fracture to help guide bone density screening efforts by clinicians in this population,” said lead author Calyani Ganesan, MD, of Stanford University.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1002/jbmr.4260

About Journal

The Journal of Bone and Mineral Research (JBMR) publishes highly impactful original manuscripts, reviews, and special articles on basic, translational and clinical investigations relevant to the musculoskeletal system and mineral metabolism. Specifically, the journal is interested in original research on the biology and physiology of skeletal tissues, interdisciplinary research spanning the musculoskeletal and other systems, including but not limited to immunology, hematology, energy metabolism, cancer biology, and neurology, and systems biology topics using large scale “-omics” approaches. The journal welcomes clinical research on the pathophysiology, treatment and prevention of osteoporosis and fractures, as well as sarcopenia, disorders of bone and mineral metabolism, and rare or genetically determined bone diseases. 

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at www.wiley.com.

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