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Study Identifies Potential Risk Factors for Cognitive Decline in Older Adults

New findings published in the Journal of the American Geriatrics Society may eventually point to different strategies for preventing cognitive decline in different groups of older adults.

Wednesday, February 5, 2020 12:01 am EST
"This was population-level research, and the next steps should be in-depth clinical and laboratory studies to fully understand the biological mechanisms underlying the associations that we observed"

In older adults with abdominal obesity (excess belly fat), sustained elevations of blood sugar were linked to a higher likelihood of experiencing cognitive decline. In older adults without abdominal obesity, the hormone adiponectin appeared to be a likely risk factor for cognitive decline.  

The study, which is published in the Journal of the American Geriatrics Society, included 478 individuals aged 65 years or older who were examined annually for 10 years, with funding from the National Institute on Aging.

The findings—which were only observed among those younger than 87 to 88 years old—may eventually point to different strategies for preventing cognitive decline in different groups of older adults.

“This was population-level research, and the next steps should be in-depth clinical and laboratory studies to fully understand the biological mechanisms underlying the associations that we observed,” said lead author Mary Ganguli, MD, MPH, of the University of Pittsburgh School of Medicine.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/jgs.16321

About Journal 

Journal of the American Geriatrics Society (JAGS) is the go-to journal for clinical aging research. We provide a diverse, interprofessional community of healthcare professionals with the latest insights on geriatrics education, clinical practice, and public policy—all supporting the high-quality, person-centered care essential to our well-being as we age. Since the publication of our first edition in 1953, JAGS has remained one of the oldest and most impactful journals dedicated exclusively to gerontology and geriatrics.

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at www.wiley.com.

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Penny Smith +44 (0) 1243 770448 (UK)
newsroom@wiley.com

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