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Statins Linked to Higher Risk of Diabetes and Skin Infections

Statins have been reported to be beneficial for infections such as pneumonia and Staphylococcus aureus bacteraemia. In the case of skin and soft tissue infections however, statin use is ironically associated with an increased risk of developing diabetes, which is a risk factor for such infections. In a British Journal of Clinical Pharmacology study, statin use for as little as 91 days was linked with elevated risks of skin and soft tissue infections and diabetes. 

Wednesday, October 9, 2019 12:01 am EDT
"We feel the results reinforce the need for clinicians to be aware that statin use may be associated with diabetes, as well as a possible increased risk of skin infections"

Statins have been reported to be beneficial for infections such as pneumonia and Staphylococcus aureus bacteraemia. In the case of skin and soft tissue infections however, statin use is ironically associated with an increased risk of developing diabetes, which is a risk factor for such infections. In a British Journal of Clinical Pharmacology study, statin use for as little as 91 days was linked with elevated risks of skin and soft tissue infections and diabetes. The increased risk of infection was seen in individuals who did and did not develop diabetes.

The study examined prescription claims from 2001 to 2011 from the Australian Department of Veterans’ Affairs.

"We feel the results reinforce the need for clinicians to be aware that statin use may be associated with diabetes, as well as a possible increased risk of skin infections," said lead author Humphrey Ko, of Curtin University in Australia.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/bcp.14077

About Journal 

Published on behalf of the British Pharmacological Society, the British Journal of Clinical Pharmacology contains papers and reports on all aspects of drug action in humans: review articles, mini review articles, original papers, commentaries, editorials and letters. The Journal enjoys a wide readership, bridging the gap between the medical profession, clinical research and the pharmaceutical industry. It also publishes research on new methods, new drugs and new approaches to treatment. The journal is recognised as one of the leading publications in its field. It is online only, publishes open access research through its OnlineOpen programme and is published monthly.

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at www.wiley.com.

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