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Many Older Adults Do Not Take Prescribed Statins Properly

In a British Journal of Clinical Pharmacology study of older adults prescribed statins, first-year nonadherence and discontinuation rates were high.

Wednesday, November 7, 2018 12:01 am EST
"The study findings highlight the need for interventions to improve statin use among older adults—in order that the benefits of statins can be realized—and recognition that certain sub-groups of people may require additional attention"

In a British Journal of Clinical Pharmacology study of older adults prescribed statins, first-year nonadherence and discontinuation rates were high.

Among 22,340 Australians aged ≥65 years who initiated statin therapy from 2014 to 2015, 55.1% were nonadherent (did not take statins for at least 80% of the intended time) in the first year after receiving their prescription, and 44.7% had discontinued altogether. Age ≥85 years, diabetes, anxiety, and being initiated on statins by a general practitioner (as opposed to a specialist) were associated with higher likelihood of nonadherence and discontinuation, while hypertension, angina, congestive heart failure, and polypharmacy (concurrent use of ≥5 drugs) were associated with a lower likelihood of nonadherence and discontinuation.

“The study findings highlight the need for interventions to improve statin use among older adults—in order that the benefits of statins can be realized—and recognition that certain sub-groups of people may require additional attention,” said senior author Professor Danny Liew, of Monash University, in Australia.

Peer Reviewed, Observational Study, Human

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/full/10.1111/bcp.13797

About Journal

Published on behalf of the British Pharmacological Society, the British Journal of Clinical Pharmacology contains papers and reports on all aspects of drug action in humans: review articles, mini review articles, original papers, commentaries, editorials and letters. The Journal enjoys a wide readership, bridging the gap between the medical profession, clinical research and the pharmaceutical industry. It also publishes research on new methods, new drugs and new approaches to treatment.

About Wiley

Wiley is a global leader in research and education. Our online scientific, technical, medical, and scholarly journals, and our digital learning, assessment, certification and student-lifecycle services and solutions help universities, academic societies, businesses, governments and individuals to achieve their academic and professional goals. For more than 200 years, we have delivered consistent performance to our stakeholders. The Company's website can be accessed at www.wiley.com.

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