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Cigarette Smoking May Contribute to Worse Outcomes in Bladder Cancer Patients

In a study of patients with muscle-invasive bladder cancer who had undergone radical cystectomy, cigarette smoking was linked with poor response to cisplatin-based chemotherapy. Also, current smokers in the study, published in BJU International, were at significantly higher risk of cancer recurrence compared with former and never smokers. 

Wednesday, January 9, 2019 12:01 am EST
"As a whole, these results suggest that physicians should have a proactive role in educating patients regarding the detrimental effect of smoking on cancer-specific and overall health outcomes"

In a study of patients with muscle-invasive bladder cancer who had undergone radical cystectomy, cigarette smoking was linked with poor response to cisplatin-based chemotherapy. Also, current smokers in the study, published in BJU International, were at significantly higher risk of cancer recurrence compared with former and never smokers.
 
The study included 58 never smokers, 87 former smokers, and 56 current smokers.

Additional research is needed to assess the impact of smoking and smoking cessation on survival in patients treated for muscle-invasive bladder cancer.

“As a whole, these results suggest that physicians should have a proactive role in educating patients regarding the detrimental effect of smoking on cancer-specific and overall health outcomes,” the authors wrote.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/full/10.1111/bju.14612 

About Journal 

BJUI aims to provide the very highest standard of research and clinical information for the urological community, promoting awareness of new advances and supporting best practice in urology.

BJUI publishes original articles, reviews, comments and educational articles on adult and paediatric urology. Clinical relevance is critical and the journal covers the entire breadth of urology under the following sections: Comments, Reviews, Urological Oncology (all areas of urological oncology as well as recent advances in diagnostic techniques), Robotics and Laparoscopy, Upper Urinary Tract, Functional Urology, Sexual Medicine, Paediatrics, Translational Science, Surgical Education and Step-by-Step.

BJUI is constantly innovating to provide the urology community with a journal that is fresh in appearance and easy to read. The journal is divided into sections and in full colour making it easier to read, and is presented with additional features and supporting discussions on our website: www.bjui.org.

About Wiley

Wiley is a global leader in research and education. Our online scientific, technical, medical, and scholarly journals, and our digital learning, assessment, certification and student-lifecycle services and solutions help universities, academic societies, businesses, governments and individuals to achieve their academic and professional goals. For more than 200 years, we have delivered consistent performance to our stakeholders. The Company's website can be accessed at www.wiley.com.

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Penny Smith +44 (0) 1243 770448 (UK)
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