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Study Reveals Seasonal Variations in Hypertensive Disorders During Pregnancy

Researchers observed seasonal variations in the risk of the hypertensive disorders of pregnancy—including gestational hypertension and preeclampsia—in a Acta Obstetricia et Gynecologica Scandinavica study of Danish women. 

Wednesday, February 5, 2020 12:01 am EST
"Our results are of great interest, as vitamin D may have caused the observed seasonal variation in the hypertensive disorders. It has long been assumed that vitamin D affects the pathogenesis of hypertensive disorders of pregnancy—including preeclampsia—and our results support this hypothesis"

Researchers observed seasonal variations in the risk of the hypertensive disorders of pregnancy—including gestational hypertension and preeclampsia—in a study of Danish women. In the Acta Obstetricia et Gynecologica Scandinavica study, the highest risk for hypertensive disorders was seen in pregnancies conceived during spring and summer.

Of 50,665 women included in the study, 8.5% were diagnosed with a hypertensive disorder of pregnancy. There appeared to be increasing risk when conceiving during the spring and early summer, peaking midsummer, and subsequently decreasing steadily during the autumn to reach a low by winter. Seasonal variations in vitamin D levels may help to explain these findings.

“Our results are of great interest, as vitamin D may have caused the observed seasonal variation in the hypertensive disorders. It has long been assumed that vitamin D affects the pathogenesis of hypertensive disorders of pregnancy—including preeclampsia—and our results support this hypothesis,” said lead author Christine Rohr Thomsen, of Aarhus University Hospital, in Denmark.

Additional Information

Link to Study: https://onlinelibrary.wiley.com/doi/10.1111/aogs.13786

About Journal 

Published monthly, Acta Obstetricia et Gynecologica Scandinavica is an international journal dedicated to providing the very latest information on the results of both clinical, basic and translational research work related to all aspects of women’s health from around the globe. The journal regularly publishes commentaries, reviews, and original articles on a wide variety of topics including: gynecology, pregnancy, birth, female urology, gynecologic oncology, fertility and reproductive biology.

About Wiley

Wiley drives the world forward with research and education. Through publishing, platforms and services, we help students, researchers, universities, and corporations to achieve their goals in an ever-changing world. For more than 200 years, we have delivered consistent performance to all of our stakeholders. The Company's website can be accessed at www.wiley.com.

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