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  • March 30, 2017
    The plasma membrane serves as a major hub for signal cascades to control crucial cellular processes. But it is a fluid medium, which makes the signaling processes difficult to monitor. Now, German scientists have designed a molecular "paintbrush" technique to trigger, control, and also monitor signaling processes. As they write in the journal Angewandte Chemie, their modular system made of light-activatable molecular building blocks can, for example, induce patterned contraction inside living...
  • March 28, 2017
    A new paper published in the Annals of Neurology reports the most common neurological diseases pose a serious annual financial burden for the nation.  The report notes that the current estimated annual cost to American society of just nine of the most common neurological diseases is staggering, totaling $789 billion in 2014 dollars. These conditions include Alzheimer's disease and other dementias, low back pain, stroke, traumatic brain injury, migraine, epilepsy, multiple sclerosis,...
  • March 28, 2017
    Investigators have shown that certain screening methods that detect the genetic material of Zika virus can be used to ensure that donated blood supplies remain free of the virus.The methods, called Zika virus nucleic acid amplification technology assays, demonstrated similar excellent sensitivities to assays currently used for screening for transfusion-transmitted viruses. The methods were substantially more sensitive than most other laboratory-developed and diagnostic Zika virus assays.“The...
  • March 27, 2017
    With no accounting or legal knowledge required, it contains practical case studies to illustrate how tax functions in the real world, for example: how the VAT on a plumber's bill all adds up; why fraudsters made a movie to throw HMRC off their scent; how a wealthy couple can pay minimal tax on a six-figure income; and the way tracing the money you paid for your iPad sheds light why the EU is demanding Apple pay billions extra in tax.Written in a conversational style, What Everyone Needs to...
  • March 27, 2017
    Drugs containing gold have been used for centuries to treat conditions like rheumatoid arthritis. In addition, they might be effective against cancer and HIV. One mechanism by which they work could occur because gold ions force the zinc ions out of zinc fingers—looped, nucleic acid binding protein domains. American researchers have characterized such “gold fingers” using ion mobility mass spectrometry. As reported in the journal Angewandte Chemie, they identified the exact gold binding sites.“...
  • March 24, 2017
    Carbapenems are among the "antibiotics of last resort" and can fight infections for which other drugs have long lost their effectiveness. However, even carbapenem-resistant pathogenic strains have emerged over the last decades. To find out whether a pathogen contains carbapenem-cleaving enzymes, the carbapenemases, Chinese scientists have developed a simple and fast assay based on a fluorescent probe and optical detection. They introduce their approach in the journal Angewandte Chemie ....
  • March 24, 2017
    A special kind of small sulfur-rich proteins, the metallothioneins, have an extraordinarily large capability for binding heavy metals. An international team of scientists has now discovered that the marine common periwinkle, which is widely considered a delicacy, contains the largest version of the protein found yet, with one additional cadmium-binding domain and a one-third higher detoxification capacity. As they report in the journal Angewandte Chemie, this feature may help the snail survive...
  • March 23, 2017
    HOBOKEN, N.J.--(BUSINESS WIRE)--John Wiley & Sons, Inc. (NYSE:JWA) (NYSE:JWB), a global research and learning company, announced that the Board of Directors has declared a quarterly cash dividend of $0.31 per share on its Class A and Class B Common Stock, payable on April 19, 2017 to shareholders of record on April 4, 2017. In June 2016, the Board of Directors increased Wiley’s quarterly cash dividend by 3.3% to $0.31 per share on its Class A and Class B...
  • March 22, 2017
    HOBOKEN, N.J.--(BUSINESS WIRE)--John Wiley & Sons, Inc., (NYSE:JWA) (NYSE:JWB) today announced the appointment of David C. Dobson, Chief Executive Officer at Digital River, to its Board of Directors, effective March 22, 2017. With more than 30 years of experience, David Dobson is an accomplished leader. Dobson joined Digital River in February 2013 as the company’s Chief Executive Officer. Dobson leads Digital River in its mission to help companies find...
  • March 22, 2017
    In a study of adults aged 40 to 90 years who were followed for 10 years, poor smell was linked with an increased risk of dying.During the study, 411 of 1774 participants (23%) died. After controlling for demographic, health-related, and cognitive confounders, each additional correctly identified odor lowered the risk of mortality by 8%. Individuals who performed at chance level on tests (indicating complete olfactory loss) were at a 19% higher risk of death than individuals with normal smell...