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  • April 07, 2017
    A new study provides reassuring information about the short-term and long-term safety of denosumab, a monoclonal antibody that is used to treat postmenopausal osteoporosis.Adverse events that had been noted in a pivotal clinical trial in women age 60 to 90 years old treated for 3 years showed no tendency to increase after a further 3 years of treatment, the study showed.In addition, women who crossed over from 3 years of placebo to 3 years of denosumab experienced no increase in adverse...
  • April 06, 2017
    Active surveillance—careful monitoring to determine if or when a cancer warrants treatment—is an increasingly prevalent choice for prostate cancer, but it’s unclear if the strategy is appropriate for men with a family history of prostate cancer. A recent analysis of the medical literature concluded that a family history of prostate cancer does not appear to increase a patient’s risk of having more aggressive prostate cancer.In the analysis, six studies found that family history does not appear...
  • April 06, 2017
    A recent study found that women with overactive bladder who received antimuscarinics were 38% more likely to be diagnosed with depressive disorder within the next 3 years than those who did not receive antimuscarinics.Although antimuscarinics can significantly depress bladder contractions and improve symptoms by blocking muscarinic receptors, studies have found that several unwanted side effects frequently occur when patients with overactive bladder receive the drugs.“This population-based...
  • April 05, 2017
    So begins the no-holds-barred exposé on the financial transactions of the world's favourite sport.Despite the global financial crisis, the size of the football transfer market has continued to rise, increasing seven-fold in value the last two decades - more than the FTSE share index.The transfer fees that clubs pay to sign top players now top €4 billion a year but, in Football's Secret Trade, authors Alex Duff and Tariq Panja show how much of the money has been flowing out of the game as a...
  • April 05, 2017
    Over two billion people globally still lack access to basic financial services - essential for improving their livelihood. The smallest amount of money can have a big impact.Part social movement and part financial strategy, impact investing offers the opportunity for investors to power change with so-called microloans. In Small Money Big Impact authors Peter Fanconi and Patrick Scheurle explain how this strategy is reshaping the way people invest, as pension funds, insurance companies,...
  • April 05, 2017
    Written not from a post-crisis perspective, rehashing tales of post-crisis fallout – but from a preventative point of view – this book traces the development of financial derivatives from bonds to credit default swaps, and shows how mathematical formulas went beyond pricing to expand their use to the point where they dwarfed the real economy. In their latest book, best-selling authors Paul Wilmott and David Orrell delve into one of the world's least-understood but highest-impact industries to...
  • April 05, 2017
    Hoboken, NJ – 5 April 2017 – John Wiley and Sons, Inc. (NYSE: JWa and JWb) is pleased to announce the launch of an exciting new open access journal, Health Science Reports. Dedicated to providing exceptional author service through swift evaluation of existing reviews, Health Science Reports will publish peer-reviewed scientifically sound research across the entire spectrum of the medical and clinical sciences.Wiley’s health sciences portfolio typically attracts more authors and articles than...
  • April 05, 2017
    A recent review of published research indicates that hearing their mother’s voice can benefit the health of preterm infants.The review included 15 studies with 512 infants from 2000 to 2015. Hearing the maternal voice, either recorded or live, was linked with the physiologic and behavioural stabilisation of preterm infants, with fewer cardiorespiratory events. There is insufficient evidence to evaluate long-term effects, however.“Preterm infants’ state becomes more stable when mothers talk and...
  • April 05, 2017
    Patients with ulcerative colitis, a chronic inflammatory bowel disease, often relapse at times of stress. In a clinical trial of 77 ulcerative colitis patients who were in clinical remission but were experiencing reduced quality of life, those assigned to 12 supervised 90-minute weekly sessions of yoga had a greater increase in quality of life and reduced activity of their colitis compared with those who were given written self-care advice.The findings suggest that regular yoga may be a...
  • April 05, 2017
    Providing pedometers, with and without providing step targets, to individuals with rheumatoid arthritis increased activity levels and decreased fatigue in a recent study.In control patients who did not receive pedometers, average daily steps declined and there was no significant change in fatigue.The findings are important because fatigue can have a significant impact on quality of life for individuals with rheumatoid arthritis, but effective and feasible treatments are limited.“Because...