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  • March 08, 2017
    A new analysis reveals a dramatic transformation in the care of patients infected with hepatitis C virus (HCV) as more effective and tolerable medications have become available. In an analysis of all HCV antiviral treatment regimens (N=107,079) initiated from 1999 through 2015 in the US Veterans Affairs national healthcare system, cure rates increased steadily from 19.2% in 1999 to 36.0% in 2010 before a remarkable increase to 90.5% in 2015. The number of patients achieving sustained...
  • March 07, 2017
    In a recent study, older individuals who had fallen and broken a hip used antidepressant and anti-anxiety medications more frequently than the general older population.The analysis measured drug levels in individuals’ blood samples, which provided investigators with a more precise measure than asking participants if they took the medications or examining their medical records. Indeed, the drugs were often present in these samples despite no information in patients’ medical records.“We were...
  • March 07, 2017
    Cannabidiol, a major component of cannabis or marijuana, appears to have effects on emotion and emotional memory, which could be helpful for treating anxiety-related and substance abuse disorders.A recent review highlights the results of studies that have investigated cannabidiol’s effects on various fear and drug memory processes.“Cannabis is best known for the 'high' caused by the chemical Tetrahydrocannabinol (THC) but it contains many other chemicals with potential medicinal...
  • March 07, 2017
    Treatment with vaginal progesterone may help reduce certain risks that can occur when mothers are pregnant with twins and have a short cervix, which is a risk factor for preterm birth.The findings come from an Ultrasound in Obstetrics and Gynecology meta-analysis of 6 studies encompassing 303 women pregnant with twins, all of whom had a cervical length of 25 mm or less in the midtrimester. Of these, 159 women received vaginal progesterone and 144 received a placebo or no treatment.Women who...
  • March 07, 2017
    HOBOKEN, N.J.--(BUSINESS WIRE)--John Wiley & Sons, Inc. (NYSE:JWa)(NYSE:JWb), a global research and learning company, today announced the following results for the third quarter of fiscal year 2017, ending January 31:       % Change $ millions...
  • March 06, 2017
    In an analysis of 243 neonatal intensive care units from 18 European countries, investigators found that only 2113 of 6648 (31.8%) newborns were assessed for prolonged, continuous pain. Daily assessments of continuous pain occurred in only 10.4% of newborns. Intensive care units with local pain management guidelines, nursing champions, and increased surgical admissions performed assessments of continuous pain more frequently than other units.“A lot of these babies are exposed to prolonged...
  • March 06, 2017
    New research indicates that dietary soy products are safe and even beneficial for women diagnosed with breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help resolve controversies over soy’s potential link to breast cancer outcomes.Soy foods are considered among the healthiest for human consumption, but their estrogen-like properties have raised concerns of a potential increased risk of breast cancer. This is because in...
  • March 03, 2017
    Treatment of Crohn’s disease and ulcerative colitis has been greatly improved by the introduction of biologic therapies such as infliximab (which targets tumour necrosis factor alpha), but at considerable cost. A recent analysis of results from 11 published studies including 829 patients shows that a new and lower-cost biosimilar for infliximab—called CT-P13 (Remsima/Inflectra)—has excellent clinical efficacy and safety.Biosimilars are highly similar versions of complex biologic therapies. CT-...
  • March 02, 2017
    An analysis of nearly 30,000 patients undergoing liver transplantation in the United States between 2008 and 2014 found elevated death and organ loss rates in the first 5 years after transplantation among recipients with the highest use of opioid pain medications while on the waiting list.Higher risks mainly emerged after the first transplant anniversary, a pattern that may in part reflect sustained opioid use. Sixty five percent of those with the highest level of opioid use on the...
  • March 01, 2017
    A new study looks at how neonicotinoid pesticides affect wood frogs, which use surface waters in agricultural environments to breed and reproduce. Neonicotinoids are widely used insecticides that are applied to a variety of crops and are relatively persistent in the environment.The study found that some neonicotinoids may cause developmental delays in the frogs, but these are not necessarily detrimental. Additional studies are needed to investigative the direct and indirect effects of...