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  • September 25, 2017
    A new study conducted in a cancer center in a state with legalized medicinal and recreational marijuana found that approximately one-quarter of surveyed patients used marijuana in the past year, mostly for physical and psychological symptoms. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed that legalization increased the likelihood for use among patients.Eight states and the District of Columbia have legalized recreational...
  • September 21, 2017
    A new study published in the Annals of Neurology found a link between head trauma in adolescence, particularly if repeated, with a raised risk of later developing multiple sclerosis. The link may be due to the initiation of an autoimmune process in the central nervous system.In the analysis of 7292 patients from Sweden with multiple sclerosis who were each matched with 10 people without the condition, one diagnosed concussion in adolescence was associated with a 22% increased likelihood of...
  • September 21, 2017
    Novel lithium electrodes coated with indium could be the basis for more powerful, longer-lasting, rechargeable batteries. The coating hinders undesirable side-reactions between the electrode and electrolyte, provide a more uniform deposition of lithium when charging, and augments storage in the lithium anode via alloying reactions between lithium and indium, as reported by American scientists in the journal Angewandte Chemie. Their success stems from the good diffusion of lithium ions along...
  • September 21, 2017
    In light of ongoing concerns by the media and the public surrounding the use of mesh in women with pelvic organ prolapse and urinary incontinence, the Pelvic Floor Society has issued a consensus statement addressing the use of mesh for the treatment of constipation and rectal prolapse (via a surgical procedure called ventral mesh rectopexy, or VMR). The Statement is published in Colorectal Disease. Mesh is a synthetic or biological material used to offer extra internal support....
  • September 20, 2017
    Fungal infections represent an increasing health crisis, especially for immune-deficient patients. American scientists now report in the journal Angewandte Chemie that specific help could be provided by small-molecule immunotherapeutics with novel mechanism of action. They developed small bifunctional molecules that simultaneously bind both chitin, a specific feature of the fungal cell wall and a molecule not found in humans, and naturally occurring human antibodies and redirect the human...
  • September 20, 2017
    In a study published in Epilepsia, young people taking anti-epileptic drugs experienced elevated rates of bone fractures and had reductions in tibial bone mineral density and lower limb muscle force.The study included 23 individuals aged 5-18 years who had been taking anti-epileptic drugs for at least 12 months. Each individual was matched to a twin, sibling, or first cousin.The findings suggest the need to further explore bone health issues in young patients taking anti-epileptic medications...
  • September 20, 2017
    The journal Andrologia has published the first report of abnormal sperm parameters in obese men based on computer aided sperm analysis. The findings suggest that clinicians may need to factor in paternal obesity prior to assisted reproduction.In the study of 1285 men, obesity was associated with lower volume of semen, sperm count, concentration, and motility, as well as greater sperm defects.“The health and reproductive performance of spermatozoa in obese men are more likely to be compromised...
  • September 20, 2017
    In a Pharmacology Research & Perspectives study, the asthma medication montelukast (trade name Singulair) was linked with neuropsychiatric reactions such as depression and aggression, with nightmares being especially frequent in children.For the study, investigators examined all adverse drug reactions on montelukast in children and adults reported to the Netherlands Pharmacovigilance Center Lareb and the WHO Global database, VigiBase®, until 2016.“Because of the high incidence of...
  • September 20, 2017
    Type 2 diabetes is associated with increased fracture risk despite normal or high bone mineral density. In a new study published in the Journal of Bone and Mineral Research, modest deficits in cortical bone—the dense outer surface of bone that forms a protective layer around the internal cavity—were demonstrated in older adults with type 2 diabetes compared with non-diabetics.Additional studies are needed to determine if addressing structural deterioration of cortical bone may reduce...
  • September 20, 2017
    A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen—an antisense oligomer that inhibits the production of certain influenza proteins—is safe and well-tolerated in healthy individuals. Additional studies on radavirsen’s potential as a treatment for influenza are warrantedIn the 56-participant trial, pharmacokinetic analyses indicated that at 8mg/kg, radavirsen is expected to be effective in the treatment of influenza.“This is the first...