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  • February 21, 2017
    Injury to the anterior cruciate ligament (ACL) in the knee frequently leads to early-onset osteoarthritis, a painful condition that can occur even if the patient has undergone ACL reconstruction to prevent its onset. A new review looks at the ability of two different reconstruction techniques to restore normal knee motion and potentially slow degenerative changes.The findings suggest that where a graft is placed on the femur is crucial for restoring joint function and knee motion and for...
  • February 20, 2017
    New research conducted in adolescent rodents provides insights on the mechanisms behind anorexia nervosa and points to a potential treatment strategy.In experiments involving food restriction and/or exercise, investigators found that the extent to which certain receptors are expressed in neurons in a particular region of the brain can influence whether an adolescent female rat develops anorexia nervosa-like behavior, such as to exercise, rather than eat, in spite of being hungry.The findings...
  • February 20, 2017
    A new analysis indicates that many cancer survivors change their prescription drug use (including skipping doses or requesting cheaper medications) for financial reasons. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides important information on the financial burden experienced by cancer survivors, suggesting non-elderly cancer survivors are particularly vulnerable to this phenomenon.Although research has shown that cancer drugs can...
  • February 16, 2017
    Patients’ mental health may affect their risk of experiencing wound-related complications after surgery, new research indicates.The study included nearly 177,000 patients in England undergoing hip replacements, knee replacements, hernia repairs, and varicose vein operations. The likelihood of experiencing wound complications after a hip replacement were 1.17-times greater for patients with moderate anxiety or depression than those without. Patients with moderate anxiety or depression also...
  • February 16, 2017
    In a study conducted in rural Uganda, use of mosquito mesh reduced the cost of groin hernia repair surgery by more than $120 (nearly €120) compared with a commercial mesh, without sacrificing effectiveness.Use of a low-cost mesh will be critical for bringing mesh repair, which is the best available method in open groin hernia repair, to countries with limited resources.“Now that we know that high quality hernia surgery can be provided at low cost with high cost effectiveness in a low...
  • February 13, 2017
    John Wiley & Sons, Inc. is now accepting submissions for the third biennial Alexis Walker Award, which honors outstanding original scholarship in the field of family science. The $5,000 award will be presented for the third time at the 79th conference of the National Council on Family Relations in November 2017 in Orlando.The award was established in 2013 in memory of Alexis Walker, an eminent scholar and pathfinder in Family Science. Alexis was a visionary leader and mentor known for the...
  • February 13, 2017
    New research indicates that about one-quarter of patients with bladder cancer treated with radical surgery on curative intent have detectable levels of tumour cells circulating in their blood. The presence of circulating tumour cells was also a predictor of cancer recurrence and death.The findings suggest that testing for circulating tumour cells in patients with bladder cancer may provide insights on which patients may need to receive aggressive treatment for their disease.“Liquid biopsies...
  • February 10, 2017
    Many patients who have their prostate glands removed as a treatment for prostate cancer complain of shortening in the length of the penis. A new study conducted in 102 men found that certain anatomical changes occur that make the length shortest 10 days after surgery, but it gradually recovers to normal values after 12 months.“The findings can help inform patients about changes in penile appearance after radical prostatectomy,” said Dr. Yoshifumi Kadono, lead author of the BJU International...
  • February 10, 2017
    Many individuals with type 2 diabetes produce abnormally low levels of a gut hormone called GLP-1, which normally stimulates insulin release from the pancreas. Now a new study shows that GLP-1 production by special cells in the gut known as L-cells can be restored in patients with recent onset type 2 diabetes following three to 12 months of treatment with liraglutide, a drug that is similar to native GLP-1.“This study shows that chronic liraglutide therapy induces a robust enhancement of GLP-1...
  • February 10, 2017
    An updated Cochrane Review published today has identified effective and safe ways to reduce unnecessary use of antibiotics in hospitals. Guidelines and policies that promote better targeting of antibiotics in patients who need them have the greatest impact when they are supported by the most effective ways to change doctors’ behaviour.Antibiotics are used to treat bacterial infections, such as pneumonia. Antibiotic resistance has become a major public health problem with some infections no...