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In Vitro Fertilization Linked with Increased Risk of Spontaneous Preterm Birth

A new analysis of published studies found an approximate 80% increased risk of spontaneous preterm birth (both before 37 and 34 weeks) when women become pregnant via in vitro fertilization (IVF) than through spontaneous conception.

Wednesday, November 8, 2017 12:01 am EST
"Placental development may play a key role in the pathogenesis of spontaneous preterm birth in IVF pregnancies. We recommend ultrasound cervical screening in this high risk group in order to apply timely preventive strategies"

A new analysis of published studies found an approximate 80% increased risk of spontaneous preterm birth (both before 37 and 34 weeks) when women become pregnant via in vitro fertilization (IVF) than through spontaneous conception. The Ultrasound in Obstetrics and Gynecology analysis included 15 studies with approximately 62,000 patients and about 3800 preterm births events.

"Placental development may play a key role in the pathogenesis of spontaneous preterm birth in IVF pregnancies. We recommend ultrasound cervical screening in this high risk group in order to apply timely preventive strategies,” said lead author Dr. Paolo Cavoretto, of the IRCCS San Raffaele Hospital, in Milan, Italy. “Future research reporting pregnancy outcomes should always emphasize etiological differentiation of preterm birth.”


Additional Information

Link to Studyhttp://onlinelibrary.wiley.com/doi/10.1002/uog.18930/full

About Journal

The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG), Ultrasound in Obstetrics & Gynecology (UOG) is an international, peer-reviewed journal. Published monthly, the journal includes original papers, case reports, reviews, Editorial and Opinion articles, and a letters column. UOG is covered by all the primary indexes including Index Medicus and Current Contents, and is read by Obstetricians, Gynecologists, Radiologists, Pediatricians, Sonographers, Midwives and Radiographers.

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