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Stimulants May Have Detrimental Effects on Muscle Control

Researchers have found that current or past use of methamphetamine or other stimulants may lead to psychomotor control deficits, or a reduced ability to control physical movement.

Thursday, April 20, 2017 12:01 am EDT
"Psychomotor deficits can make it difficult to perform everyday tasks, and the detection of psychomotor deficiencies might be considered an early marker for movement disorders"

Researchers have found that current or past use of methamphetamine or other stimulants may lead to psychomotor control deficits, or a reduced ability to control physical movement.

Study participants were asked to hold their dominant arm in various positions, one at a time, and maintain each position for 60 seconds, with a 30-second rest between each. Investigators found impairments in terms of both tremor and arm-droop in heavy stimulant users. Tremor, but not arm-droop, persisted for at least 18 months following withdrawal from stimulant use.

“Psychomotor deficits can make it difficult to perform everyday tasks, and the detection of psychomotor deficiencies might be considered an early marker for movement disorders,” said Prof. Andrew Parrott, senior author of The Journal of Clinical Pharmacology study.


Additional Information

Link to Study: http://doi.wiley.com/10.1002/jcph.925

About Journal

The Journal of Clinical Pharmacology (JCP) is the flagship publication of the American College of Clinical Pharmacology. Published since 1961, the journal has been providing readers with access to original research, special reviews, commentaries, and case reports on all phases of drug development. A monthly, international peer-reviewed journal, The Journal of Clinical Pharmacology (JCP) transitioned to an online-only format beginning in 2013.

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